Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function
Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background ABCA4, the gene implicated in Stargardt disease (STGD1), contains 50 exons, of which 17 contain multiples of three nucleotides. The impact of in-frame exon skipping is yet to be determined. Antisense oligonucleotides (AONs) have been investigated in Usher syndrome-associated genes to induce skipping of in-frame exons carrying severe vari...
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Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function
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TN_cdi_doaj_primary_oai_doaj_org_article_cddd2e0c77e44ce5a473e43acb5cf400
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cddd2e0c77e44ce5a473e43acb5cf400
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-023-04406-x
