The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therap...
The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy
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England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
A prolonged therapy, primarily responsible for development of drug resistance by
(Mtb), obligates any new TB regimen to not only reduce treatment duration but also escape pathogen resistance mechanisms. With the aim of harnessing the host response in providing support to existing regimens, we used sertraline (SRT) to stunt the pro-pathogenic typ...
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The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_cdf9d3fd501e4b1084c83f228b8a45b1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cdf9d3fd501e4b1084c83f228b8a45b1
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.64834