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The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therap...

The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therap...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cdf9d3fd501e4b1084c83f228b8a45b1

The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy

About this item

Full title

The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2023-01, Vol.12

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

A prolonged therapy, primarily responsible for development of drug resistance by
(Mtb), obligates any new TB regimen to not only reduce treatment duration but also escape pathogen resistance mechanisms. With the aim of harnessing the host response in providing support to existing regimens, we used sertraline (SRT) to stunt the pro-pathogenic typ...

Alternative Titles

Full title

The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cdf9d3fd501e4b1084c83f228b8a45b1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cdf9d3fd501e4b1084c83f228b8a45b1

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.64834

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