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An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce1039e563874f36976d04d69d91cc82

An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

About this item

Full title

An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-11, Vol.13 (1), p.21038-21038, Article 21038

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glucose, a primary fuel source under homeostatic conditions, is transported into cells by membrane transporters such as glucose transporter 1 (GLUT1). Due to its essential role in maintaining energy homeostasis, dysregulation of GLUT1 expression and function can adversely affect many physiological processes in the body. This has implications in a w...

Alternative Titles

Full title

An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ce1039e563874f36976d04d69d91cc82

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce1039e563874f36976d04d69d91cc82

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-48361-5

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