ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mi...
ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice
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United States: American Society for Clinical Investigation
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English
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United States: American Society for Clinical Investigation
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Pregnancy is associated with substantial physiological changes of the heart, and disruptions in these processes can lead to peripartum cardiomyopathy (PPCM). The molecular processes that cause physiological and pathological changes in the heart during pregnancy are not well characterized. Here, we show that mTORc1 was activated in pregnancy to faci...
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ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_ce1ae0e9ad7f4a358703ee95ae7ff468
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce1ae0e9ad7f4a358703ee95ae7ff468
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI154491