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Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar a...

Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce2e28e8dfd64f55b561f5a692c30fa6

Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury

About this item

Full title

Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2018-08, Vol.6 (1), p.73-18, Article 73

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

After spinal cord injury (SCI), neutrophil elastase (NE) released at injury site disrupts vascular endothelium integrity and stabilization. Angiopoietins (ANGPTs) are vascular growth factors that play an important role in vascular stabilization. We hypothesized that neutrophil elastase is one of the key determinants of vascular endothelium disrupti...

Alternative Titles

Full title

Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ce2e28e8dfd64f55b561f5a692c30fa6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce2e28e8dfd64f55b561f5a692c30fa6

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-018-0576-3

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