Tobacco-induced hyperglycemia promotes lung cancer progression via cancer cell-macrophage interactio...
Tobacco-induced hyperglycemia promotes lung cancer progression via cancer cell-macrophage interaction through paracrine IGF2/IR/NPM1-driven PD-L1 expression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Tobacco smoking (TS) is implicated in lung cancer (LC) progression through the development of metabolic syndrome. However, direct evidence linking metabolic syndrome to TS-mediated LC progression remains to be established. Our findings demonstrate that 4-(methylnitrosamino)−1-(3-pyridyl)−1-butanone and benzo[a]pyrene (NNK and BaP; NB), components o...
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Full title
Tobacco-induced hyperglycemia promotes lung cancer progression via cancer cell-macrophage interaction through paracrine IGF2/IR/NPM1-driven PD-L1 expression
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TN_cdi_doaj_primary_oai_doaj_org_article_ce50cebb753f46e7b12fda546522af2e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce50cebb753f46e7b12fda546522af2e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49199-9
