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Advances of DNA Methylation in Lung Cancer

Advances of DNA Methylation in Lung Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce5ab63c141b46f3828720dea3ee3882

Advances of DNA Methylation in Lung Cancer

About this item

Full title

Advances of DNA Methylation in Lung Cancer

Author / Creator

Publisher

Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association

Journal title

Zhongguo fei ai za zhi, 2010-11, Vol.13 (11), p.1074-1078

Language

Chinese

Formats

Publication information

Publisher

Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association

More information

Scope and Contents

Contents

html>目前,肺癌仍为人类因癌症死亡的主要原因[1],全世界每年有150万人死于肺癌。临床上肺癌患者就诊时大多已属中晚期,错失手术机会,5年生存率不足15%[2],肺癌如此高的死亡率与缺乏早期检测手段及欠佳的治疗措施有关,要想提高生存率,只有通过早期发现、早期诊断和早期手术治疗等来实现。目前虽然对肺癌形成及发生发展机制已进行了大量研究与探索,但其确切机制尚未明确。许多研究[3-5]表明,DNA甲基化与多种肿瘤的发生发展密切相关,是肿瘤发生发展的重要机制之一。在肺癌发生发展过程中,DNA甲基化修饰异常也扮演着重要角色。了解DNA甲基化修饰异常在肺癌发生发展中的机制,将有助于肺癌患者的早期发现、早期诊断、早期治疗并改善预后。本文就DNA甲基化修饰异常在肺癌中的研究进展综述如下。 1 DNA甲基...

Alternative Titles

Full title

Advances of DNA Methylation in Lung Cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ce5ab63c141b46f3828720dea3ee3882

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce5ab63c141b46f3828720dea3ee3882

Other Identifiers

ISSN

1009-3419

E-ISSN

1999-6187

DOI

10.3779/cjlc.v13i11.1877

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