RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendr...
RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells
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Author / Creator
Tullett, Kirsteen M , Tan, Peck Szee , Park, Hae-Young , Schittenhelm, Ralf B , Michael, Nicole , Li, Rong , Policheni, Antonia N , Gruber, Emily , Huang, Cheng , Fulcher, Alex J , Danne, Jillian C , Czabotar, Peter E , Wakim, Linda M , Mintern, Justine D , Ramm, Georg , Radford, Kristen J , Caminschi, Irina , O'Keeffe, Meredith , Villadangos, Jose A , Wright, Mark D , Blewitt, Marnie E , Heath, William R , Shortman, Ken , Purcell, Anthony W , Nicola, Nicos A , Zhang, Jian-Guo and Lahoud, Mireille H
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
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Publication information
Publisher
England: eLife Science Publications, Ltd
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More information
Scope and Contents
Contents
The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8
T cell immune responses. Here, we show that this process is regulated by E3 ubiquitin ligase RNF41 and define a new ubiquitin-mediated mechanism for regulation of Clec9A, reflecting the unique properti...
Alternative Titles
Full title
RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells
Authors, Artists and Contributors
Author / Creator
Tan, Peck Szee
Park, Hae-Young
Schittenhelm, Ralf B
Michael, Nicole
Li, Rong
Policheni, Antonia N
Gruber, Emily
Huang, Cheng
Fulcher, Alex J
Danne, Jillian C
Czabotar, Peter E
Wakim, Linda M
Mintern, Justine D
Ramm, Georg
Radford, Kristen J
Caminschi, Irina
O'Keeffe, Meredith
Villadangos, Jose A
Wright, Mark D
Blewitt, Marnie E
Heath, William R
Shortman, Ken
Purcell, Anthony W
Nicola, Nicos A
Zhang, Jian-Guo
Lahoud, Mireille H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ce7301ac4e2c47ffba46b495f1882e5b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce7301ac4e2c47ffba46b495f1882e5b
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.63452
