Trefoil factors share a lectin activity that defines their role in mucus
Trefoil factors share a lectin activity that defines their role in mucus
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The mucosal epithelium secretes a host of protective disulfide-rich peptides, including the trefoil factors (TFFs). The TFFs increase the viscoelasticity of the mucosa and promote cell migration, though the molecular mechanisms underlying these functions have remained poorly defined. Here, we demonstrate that all TFFs are divalent lectins that reco...
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Full title
Trefoil factors share a lectin activity that defines their role in mucus
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TN_cdi_doaj_primary_oai_doaj_org_article_cf2cbf05a6394844b850bf051a2a3963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf2cbf05a6394844b850bf051a2a3963
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16223-7
