Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Single-cell multi-omics are powerful means to study cell-to-cell heterogeneity. Here, we present a single-tube, bisulfite-free method for the simultaneous, genome-wide analysis of DNA methylation and genetic variants in single cells: epigenomics and genomics of single cells analyzed by restriction (epi-gSCAR). By applying this method, we obtained D...
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Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
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TN_cdi_doaj_primary_oai_doaj_org_article_cf2fb844146243e2a468922f8c181aef
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf2fb844146243e2a468922f8c181aef
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-01661-w
