New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strate...
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy
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Publisher
England: Taylor & Francis Ltd
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Language
English
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England: Taylor & Francis Ltd
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PIN1 is considered as a therapeutic target for a wide variety of tumours. However, most of known inhibitors are devoid of cellular activity despite their good enzyme inhibitory profile. Hence, the lack of effective compounds for the clinic makes the identification of novel PIN1 inhibitors a hot topic in the medicinal chemistry field. In this work,...
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New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy
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TN_cdi_doaj_primary_oai_doaj_org_article_cf62bc6b195e4bc6b05154bb0957ad8b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf62bc6b195e4bc6b05154bb0957ad8b
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ISSN
1475-6366
E-ISSN
1475-6374
DOI
10.1080/14756366.2021.1979970
