HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting c...
HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Immune responses primed by endogenous heat shock proteins, specifically gp96, can be varied, and mechanisms controlling these responses have not been defined. Immunization with low doses of gp96 primes T helper type 1 (Th1) immune responses, whereas high-dose immunization primes responses characterized by regulatory T (Treg) cells and immunosuppres...
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Full title
HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting cells
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TN_cdi_doaj_primary_oai_doaj_org_article_cf78ebbf481d47ad9ecf5de60d0357a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf78ebbf481d47ad9ecf5de60d0357a8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15648
