DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections...
DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease
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Author / Creator
Masato, Anna , Plotegher, Nicoletta , Terrin, Francesca , Sandre, Michele , Faustini, Gaia , Thor, Andrea , Adams, Stephen , Berti, Giulia , Cogo, Susanna , De Lazzari, Federica , Fontana, Camilla Maria , Martinez, Paul Anthony , Strong, Randy , Bandopadhyay, Rina , Bisaglia, Marco , Bellucci, Arianna , Greggio, Elisa , Dalla Valle, Luisa , Boassa, Daniela and Bubacco, Luigi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Dopamine dyshomeostasis has been acknowledged among the determinants of nigrostriatal neuron degeneration in Parkinson’s disease (PD). Several studies in experimental models and
postmortem
PD patients underlined increasing levels of the dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL), which is highly reactive towards proteins. DOP...
Alternative Titles
Full title
DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease
Authors, Artists and Contributors
Author / Creator
Plotegher, Nicoletta
Terrin, Francesca
Sandre, Michele
Faustini, Gaia
Thor, Andrea
Adams, Stephen
Berti, Giulia
Cogo, Susanna
De Lazzari, Federica
Fontana, Camilla Maria
Martinez, Paul Anthony
Strong, Randy
Bandopadhyay, Rina
Bisaglia, Marco
Bellucci, Arianna
Greggio, Elisa
Dalla Valle, Luisa
Boassa, Daniela
Bubacco, Luigi
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cf79d21672c5410c9590d5ad6ce4d10a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf79d21672c5410c9590d5ad6ce4d10a
Other Identifiers
ISSN
2373-8057
E-ISSN
2373-8057
DOI
10.1038/s41531-023-00485-1