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DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections...

DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf79d21672c5410c9590d5ad6ce4d10a

DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease

About this item

Full title

DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease

Publisher

London: Nature Publishing Group UK

Journal title

NPJ Parkinson's Disease, 2023-03, Vol.9 (1), p.42-42, Article 42

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dopamine dyshomeostasis has been acknowledged among the determinants of nigrostriatal neuron degeneration in Parkinson’s disease (PD). Several studies in experimental models and
postmortem
PD patients underlined increasing levels of the dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL), which is highly reactive towards proteins. DOP...

Alternative Titles

Full title

DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cf79d21672c5410c9590d5ad6ce4d10a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf79d21672c5410c9590d5ad6ce4d10a

Other Identifiers

ISSN

2373-8057

E-ISSN

2373-8057

DOI

10.1038/s41531-023-00485-1

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