Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblast...
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity
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England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Circulating fibrocytes are an important source of fibroblasts and myofibroblasts, which are involved in fibrotic processes, including systemic sclerosis (SSc). The study aimed to investigate the effect of nintedanib (a tyrosine kinase inhibitor) in inhibiting the in vitro transition of circulating SSc fibrocytes into myofibroblasts and their pro-fi...
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Full title
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity
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TN_cdi_doaj_primary_oai_doaj_org_article_cf85bdd47fd94d59a75569cba95c43d6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf85bdd47fd94d59a75569cba95c43d6
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ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-021-02555-2
