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Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf945f75a36f4d35b18c7f8a95f28d2f

Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

About this item

Full title

Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

Publisher

Switzerland: MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2020-04, Vol.10 (4), p.660

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The functions of the annexin family of proteins involve binding to Ca
, lipid membranes, other proteins, and RNA, and the annexins share a common folded core structure at the C terminus. Annexin A11 (AnxA11) has a long N-terminal region, which is predicted to be disordered, binds RNA, and forms membraneless organelles involved in neuronal transp...

Alternative Titles

Full title

Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cf945f75a36f4d35b18c7f8a95f28d2f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf945f75a36f4d35b18c7f8a95f28d2f

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom10040660

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