961 Preliminary results of a phase 2 study of intratumoral administration of BO-112 with pembrolizum...
961 Preliminary results of a phase 2 study of intratumoral administration of BO-112 with pembrolizumab in patients with advanced melanoma that have progressive disease on anti-PD-1-based therapy
About this item
Full title
Author / Creator
Rodas, Iván Márquez , Saiag, Philippe , Merino, Luis de la Cruz , Dutriaux, Caroline , Rodríguez-Moreno, Juan , Robert, Caroline , Arance, Ana , Álvarez, Eduardo Castañón , Cerezuela-Fuentes, Pablo , Montaudie, Henry , Sanmamed, Miguel , Cao, María González , Charles, Julie , López Criado, María Pilar , Berrocal, Alfonso , Miguel, Enrique de , Funk-Brentano, Elisa , Prey, Sorilla , Huertas, Roberto , Abreu, Delvys Rodríguez , Couselo, Eva Muñoz , Martin-Liberal, Juan , López, Javier Sánchez , Escuin-Ordinas, Helena , Quintero, Marisol , Maciá, Sonia , Chaney, Marya and Dalle, Stephane
Publisher
London: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundIntratumoral immunotherapies are being tested in different solid tumors. They trigger local and systemic responses.1 2 BO-112 is a double stranded RNA nanoplexed with polyethyleneimine (PEI), which mimics a viral infection and mobilizes the immune system.In preclinical models and in a first in human clinical trial BO-112 activated dendrit...
Alternative Titles
Full title
961 Preliminary results of a phase 2 study of intratumoral administration of BO-112 with pembrolizumab in patients with advanced melanoma that have progressive disease on anti-PD-1-based therapy
Authors, Artists and Contributors
Author / Creator
Saiag, Philippe
Merino, Luis de la Cruz
Dutriaux, Caroline
Rodríguez-Moreno, Juan
Robert, Caroline
Arance, Ana
Álvarez, Eduardo Castañón
Cerezuela-Fuentes, Pablo
Montaudie, Henry
Sanmamed, Miguel
Cao, María González
Charles, Julie
López Criado, María Pilar
Berrocal, Alfonso
Miguel, Enrique de
Funk-Brentano, Elisa
Prey, Sorilla
Huertas, Roberto
Abreu, Delvys Rodríguez
Couselo, Eva Muñoz
Martin-Liberal, Juan
López, Javier Sánchez
Escuin-Ordinas, Helena
Quintero, Marisol
Maciá, Sonia
Chaney, Marya
Dalle, Stephane
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cfa232992c194eb9b490f0ff34e0deec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cfa232992c194eb9b490f0ff34e0deec
Other Identifiers
E-ISSN
2051-1426
DOI
10.1136/jitc-2021-SITC2021.961
