Cas9-derived peptides presented by MHC Class II that elicit proliferation of CD4+ T-cells
Cas9-derived peptides presented by MHC Class II that elicit proliferation of CD4+ T-cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
CRISPR–Cas9 mediated genome editing offers unprecedented opportunities for treating human diseases. There are several reports that demonstrate pre-existing immune responses to Cas9 which may have implications for clinical development of CRISPR-Cas9 mediated gene therapy. Here we use 209 overlapping peptides that span the entire sequence of Staphylo...
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Cas9-derived peptides presented by MHC Class II that elicit proliferation of CD4+ T-cells
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TN_cdi_doaj_primary_oai_doaj_org_article_cfab9360e97b4aa380519906ce6d7273
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cfab9360e97b4aa380519906ce6d7273
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25414-9