A combined spatial score of granzyme B and CD68 surpasses CD8 as an independent prognostic factor in...
A combined spatial score of granzyme B and CD68 surpasses CD8 as an independent prognostic factor in TNM stage II colorectal cancer
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Previous assessments of peritumoral inflammatory infiltrate in colorectal cancer (CRC) have focused on the role of CD8.sup.+ T lymphocytes. We sought to compare the prognostic value of CD8 with downstream indicators of active immune cell function, specifically granzyme B (GZMB) and CD68 in the tumour microenvironment. Methods Immunohisto...
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A combined spatial score of granzyme B and CD68 surpasses CD8 as an independent prognostic factor in TNM stage II colorectal cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_cfbc8f10d8a7441da59d8e0291493ca3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cfbc8f10d8a7441da59d8e0291493ca3
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-022-10048-x
