Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cance...
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
About this item
Full title
Author / Creator
Pelon, Floriane , Bourachot, Brigitte , Kieffer, Yann , Magagna, Ilaria , Mermet-Meillon, Fanny , Bonnet, Isabelle , Costa, Ana , Givel, Anne-Marie , Attieh, Youmna , Barbazan, Jorge , Bonneau, Claire , Fuhrmann, Laetitia , Descroix, Stéphanie , Vignjevic, Danijela , Silberzan, Pascal , Parrini, Maria Carla , Vincent-Salomon, Anne and Mechta-Grigoriou, Fatima
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Although fibroblast heterogeneity is recognized in primary tumors, both its characterization in and its impact on metastases remain unknown. Here, combining flow cytometry, immunohistochemistry and RNA-sequencing on breast cancer samples, we identify four Cancer-Associated Fibroblast (CAF) subpopulations in metastatic lymph nodes (LN). Two myofibro...
Alternative Titles
Full title
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
Authors, Artists and Contributors
Author / Creator
Bourachot, Brigitte
Kieffer, Yann
Magagna, Ilaria
Mermet-Meillon, Fanny
Bonnet, Isabelle
Costa, Ana
Givel, Anne-Marie
Attieh, Youmna
Barbazan, Jorge
Bonneau, Claire
Fuhrmann, Laetitia
Descroix, Stéphanie
Vignjevic, Danijela
Silberzan, Pascal
Parrini, Maria Carla
Vincent-Salomon, Anne
Mechta-Grigoriou, Fatima
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cffe5431806244e5b3bdeb1e1726578f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cffe5431806244e5b3bdeb1e1726578f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-14134-w
