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Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Pa...

Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Pa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cfff42f7ea5e4e1ab38d4f5ab4bbf112

Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

About this item

Full title

Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-10, Vol.13 (1), p.17697-17697, Article 17697

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dopamine transmission has been implicated in motor and cognitive function. In Parkinson’s disease (PD), dopamine replacement using the precursor drug
l
-DOPA is the predominant treatment approach, but long-term exposure leads to the onset of dyskinesias (LIDs). Chronic
l
-DOPA exposure has been associated with changes in gene expression...

Alternative Titles

Full title

Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cfff42f7ea5e4e1ab38d4f5ab4bbf112

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cfff42f7ea5e4e1ab38d4f5ab4bbf112

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-44869-y

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