A microRNA signature of toxic extrasynaptic N-methyl-D-aspartate (NMDA) receptor signaling
A microRNA signature of toxic extrasynaptic N-methyl-D-aspartate (NMDA) receptor signaling
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
The cellular consequences of N-Methyl-D-Aspartate receptor (NMDAR) stimulation depend on the receptors’ subcellular localization. Synaptic NMDARs promote plasticity and survival whereas extrasynaptic NMDARs mediate excitotoxicity and contribute to cell death in neurodegenerative diseases. The mechanisms that couple activation of extrasynaptic NMDAR...
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Full title
A microRNA signature of toxic extrasynaptic N-methyl-D-aspartate (NMDA) receptor signaling
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TN_cdi_doaj_primary_oai_doaj_org_article_d007fae61eb245b79d5afc68f45e4648
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d007fae61eb245b79d5afc68f45e4648
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ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/s13041-020-0546-0
