Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection agains...
Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria
About this item
Full title
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
CelTOS is a malaria vaccine antigen that is conserved in
Plasmodium
and other apicomplexan parasites and plays a role in cell-traversal. The structural basis and mechanisms of CelTOS-induced protective immunity to parasites are unknown. Here, CelTOS-specific monoclonal antibodies (mAbs) 7g7 and 4h12 demonstrated multistage activity, protectin...
Alternative Titles
Full title
Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d0429fc0473748f896d3001e25c1ffd9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0429fc0473748f896d3001e25c1ffd9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51701-2
