Type I interferon (IFN)-inducible Absent in Melanoma 2 proteins in neuroinflammation: implications f...
Type I interferon (IFN)-inducible Absent in Melanoma 2 proteins in neuroinflammation: implications for Alzheimer's disease
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Cumulative evidence indicates that activation of innate immune responses in the central nervous system (CNS) induces the expression of type 1 interferons (T1 IFNs), a family of cytokines. The T1 IFNs (IFN-α/β), through activation of the JAK/STAT-signaling in microglia, astrocytes, and neurons, induce the expression of IFN-inducible proteins, which...
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Full title
Type I interferon (IFN)-inducible Absent in Melanoma 2 proteins in neuroinflammation: implications for Alzheimer's disease
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TN_cdi_doaj_primary_oai_doaj_org_article_d051d20fbd8740a6af21c4cca4103e01
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d051d20fbd8740a6af21c4cca4103e01
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-019-1639-5
