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Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice

Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0530d03ea864df787baf980d668a0d4

Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice

About this item

Full title

Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-05, Vol.15 (1), p.4393-4393, Article 4393

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Whether intestinal Leucine-rich repeat containing G-protein-coupled receptor 4 (LGR4) impacts nutrition absorption and energy homeostasis remains unknown. Here, we report that deficiency of
Lgr4
(
Lgr4
iKO
) in intestinal epithelium decreased the proportion of enterocytes selective for long-chain fatty acid absorption, leading to red...

Alternative Titles

Full title

Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d0530d03ea864df787baf980d668a0d4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0530d03ea864df787baf980d668a0d4

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-48622-5

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