Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3...
Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors
About this item
Full title
Author / Creator
Natoli, Marina , Hatje, Klas , Gulati, Pratiksha , Junker, Fabian , Herzig, Petra , Jiang, Zhiwen , Davydov, Iakov I , Germann, Markus , Trüb, Marta , Marbach, Daniel , Zwick, Adrian , Weber, Patrick , Seeber, Stefan , Wiese, Mark , Lardinois, Didier , Heinzelmann-Schwarz, Viola , Rosenberg, Robert , Tietze, Lothar , Mertz, Kirsten D , Umaña, Pablo , Klein, Christian , Codarri-Deak, Laura , Kao, Henry and Zippelius, Alfred
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundNext-generation cancer immunotherapies are designed to broaden the therapeutic repertoire by targeting new immune checkpoints including lymphocyte-activation gene 3 (LAG-3) and T cell immunoglobulin and mucin-domain containing-3 (TIM-3). Yet, the molecular and cellular mechanisms by which either receptor functions to mediate its inhibitor...
Alternative Titles
Full title
Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors
Authors, Artists and Contributors
Author / Creator
Hatje, Klas
Gulati, Pratiksha
Junker, Fabian
Herzig, Petra
Jiang, Zhiwen
Davydov, Iakov I
Germann, Markus
Trüb, Marta
Marbach, Daniel
Zwick, Adrian
Weber, Patrick
Seeber, Stefan
Wiese, Mark
Lardinois, Didier
Heinzelmann-Schwarz, Viola
Rosenberg, Robert
Tietze, Lothar
Mertz, Kirsten D
Umaña, Pablo
Klein, Christian
Codarri-Deak, Laura
Kao, Henry
Zippelius, Alfred
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d05c988c40044c0488968cfb22947d69
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d05c988c40044c0488968cfb22947d69
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2022-005548
