Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular pro...
Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Small heat shock proteins (sHsp) constitute an evolutionary conserved yet diverse family of chaperones acting as first line of defence against proteotoxic stress. sHsps coaggregate with misfolded proteins but the molecular basis and functional implications of these interactions, as well as potential sHsp specific differences, are poorly explored. I...
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Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding
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TN_cdi_doaj_primary_oai_doaj_org_article_d064b25e594849efb795495f07d85f93
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d064b25e594849efb795495f07d85f93
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms13673