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Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular pro...

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular pro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d064b25e594849efb795495f07d85f93

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

About this item

Full title

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-11, Vol.7 (1), p.13673-13673, Article 13673

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Small heat shock proteins (sHsp) constitute an evolutionary conserved yet diverse family of chaperones acting as first line of defence against proteotoxic stress. sHsps coaggregate with misfolded proteins but the molecular basis and functional implications of these interactions, as well as potential sHsp specific differences, are poorly explored. I...

Alternative Titles

Full title

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d064b25e594849efb795495f07d85f93

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d064b25e594849efb795495f07d85f93

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms13673

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