Ribozyme Activity of RNA Nonenzymatically Polymerized from 3′,5′-Cyclic GMP
Ribozyme Activity of RNA Nonenzymatically Polymerized from 3′,5′-Cyclic GMP
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Contents
3′,5′-Cyclic GMP spontaneously nonenzymatically polymerizes in a base-catalyzed reaction affording G oligonucleotides. When reacted with fully or partially sequence-complementary RNA (oligo C), the abiotically generated oligo G RNA displays a typical ribozyme activity consisting of terminal ligation accompanied by cleavage of an internal phosphate...
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Full title
Ribozyme Activity of RNA Nonenzymatically Polymerized from 3′,5′-Cyclic GMP
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TN_cdi_doaj_primary_oai_doaj_org_article_d0aff2b0e2664e318b9a2a67353e341b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0aff2b0e2664e318b9a2a67353e341b
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ISSN
1099-4300
E-ISSN
1099-4300
DOI
10.3390/e15125362
