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Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells

Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0b260fa47e44d809b279ae3873a1f18

Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells

About this item

Full title

Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells

Publisher

England: BioMed Central

Journal title

Cellular & molecular biology letters, 2025-01, Vol.30 (1), p.3-40, Article 3

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Metabolism is error prone. For instance, the reduced forms of the central metabolic cofactors nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH), can be converted into redox-inactive products, NADHX and NADPHX, through enzymatically catalyzed or spontaneous hydration. The metabolite repair enzymes NAXD...

Alternative Titles

Full title

Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d0b260fa47e44d809b279ae3873a1f18

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0b260fa47e44d809b279ae3873a1f18

Other Identifiers

ISSN

1689-1392,1425-8153

E-ISSN

1689-1392

DOI

10.1186/s11658-024-00681-8

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