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Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0b59c5a040d41be8c7d87c9047d2474

Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

About this item

Full title

Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-09, Vol.12 (1), p.5214-17, Article 5214

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dyslipidemia and resulting lipotoxicity are pathologic signatures of metabolic syndrome and type 2 diabetes. Excess lipid causes cell dysfunction and induces cell death through pleiotropic mechanisms that link to oxidative stress. However, pathways that regulate the response to metabolic stress are not well understood. Herein, we show that disrupti...

Alternative Titles

Full title

Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d0b59c5a040d41be8c7d87c9047d2474

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0b59c5a040d41be8c7d87c9047d2474

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-25457-y

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