Pluripotency-independent induction of human trophoblast stem cells from fibroblasts
Pluripotency-independent induction of human trophoblast stem cells from fibroblasts
About this item
Full title
Author / Creator
Naama, Moriyah , Rahamim, Moran , Zayat, Valery , Sebban, Shulamit , Radwan, Ahmed , Orzech, Dana , Lasry, Rachel , Ifrah, Annael , Jaber, Mohammad , Sabag, Ofra , Yassen, Hazar , Khatib, Areej , Epsztejn-Litman, Silvina , Novoselsky-Persky, Michal , Makedonski, Kirill , Deri, Noy , Goldman-Wohl, Debra , Cedar, Howard , Yagel, Simcha , Eiges, Rachel and Buganim, Yosef
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Human trophoblast stem cells (hTSCs) can be derived from embryonic stem cells (hESCs) or be induced from somatic cells by OCT4, SOX2, KLF4 and MYC (OSKM). Here we explore whether the hTSC state can be induced independently of pluripotency, and what are the mechanisms underlying its acquisition. We identify GATA3, OCT4, KLF4 and MYC (GOKM) as a comb...
Alternative Titles
Full title
Pluripotency-independent induction of human trophoblast stem cells from fibroblasts
Authors, Artists and Contributors
Author / Creator
Rahamim, Moran
Zayat, Valery
Sebban, Shulamit
Radwan, Ahmed
Orzech, Dana
Lasry, Rachel
Ifrah, Annael
Jaber, Mohammad
Sabag, Ofra
Yassen, Hazar
Khatib, Areej
Epsztejn-Litman, Silvina
Novoselsky-Persky, Michal
Makedonski, Kirill
Deri, Noy
Goldman-Wohl, Debra
Cedar, Howard
Yagel, Simcha
Eiges, Rachel
Buganim, Yosef
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d0c4b6ee563d4a668d24fbf8c84f012e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0c4b6ee563d4a668d24fbf8c84f012e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39104-1
