Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an...
Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an Iridium Photosensitizer
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Author / Creator
Li, Shumeng , Yuan, Hao , Yang, Xiu-Zhi , Xu, Xinyu , Yu, Wenhao , Wu, Yanping , Yao, Shankun , Xie, Jin , He, Weijiang , Guo, Zijian and Chen, Yuncong
Publisher
United States: American Chemical Society
Journal title
Language
English
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Publication information
Publisher
United States: American Chemical Society
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Scope and Contents
Contents
Mitochondrial targeting has emerged as an attractive method for antitumor treatment. However, most of the mitochondria targeted drugs focused on inhibiting tumor cells, while their potential for activation of immune responses in the tumor microenvironment has rarely been described. In this study, we report a photosensitive iridium complex MitoIrL2,...
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Full title
Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an Iridium Photosensitizer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d0c6218b3a634d7e883962d139abbb81
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0c6218b3a634d7e883962d139abbb81
Other Identifiers
ISSN
2374-7943
E-ISSN
2374-7951
DOI
10.1021/acscentsci.4c02156