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Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an...

Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0c6218b3a634d7e883962d139abbb81

Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an Iridium Photosensitizer

About this item

Full title

Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an Iridium Photosensitizer

Publisher

United States: American Chemical Society

Journal title

ACS central science, 2025-03, Vol.11 (3), p.441-451

Language

English

Formats

Publication information

Publisher

United States: American Chemical Society

More information

Scope and Contents

Contents

Mitochondrial targeting has emerged as an attractive method for antitumor treatment. However, most of the mitochondria targeted drugs focused on inhibiting tumor cells, while their potential for activation of immune responses in the tumor microenvironment has rarely been described. In this study, we report a photosensitive iridium complex MitoIrL2,...

Alternative Titles

Full title

Synergistic Antitumor Immunotherapy via Mitochondria Regulation in Macrophages and Tumor Cells by an Iridium Photosensitizer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d0c6218b3a634d7e883962d139abbb81

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0c6218b3a634d7e883962d139abbb81

Other Identifiers

ISSN

2374-7943

E-ISSN

2374-7951

DOI

10.1021/acscentsci.4c02156

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