Histone demethylase KDM4C controls tumorigenesis of glioblastoma by epigenetically regulating p53 an...
Histone demethylase KDM4C controls tumorigenesis of glioblastoma by epigenetically regulating p53 and c-Myc
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Glioblastoma is the most lethal brain tumor and its pathogenesis remains incompletely understood. KDM4C is a histone H3K9 demethylase that contributes to epigenetic regulation of both oncogene and tumor suppressor genes and is often overexpressed in human tumors, including glioblastoma. However, KDM4C’s roles in glioblastoma and the underlying mole...
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Histone demethylase KDM4C controls tumorigenesis of glioblastoma by epigenetically regulating p53 and c-Myc
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TN_cdi_doaj_primary_oai_doaj_org_article_d0de556d57c8492ca33374883b95cc94
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0de556d57c8492ca33374883b95cc94
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2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-03380-2
