A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nu...
A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
High-throughput sequencing such as those provided by Illumina are an efficient way to understand sequence variation within viral populations. However, challenges exist in distinguishing process-introduced error from biological variance, which significantly impacts our ability to identify sub-consensus single-nucleotide variants (SNVs). Here we have...
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Full title
A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations
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TN_cdi_doaj_primary_oai_doaj_org_article_d1036efccba94d11a66b4fb4761e7d1a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1036efccba94d11a66b4fb4761e7d1a
Other Identifiers
ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v12101187
