Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors
Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors
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Author / Creator
Marcu, Ana , Schlosser, Andreas , Keupp, Anne , Trautwein, Nico , Johann, Pascal , Wölfl, Matthias , Lager, Johanna , Monoranu, Camelia Maria , Walz, Juliane S , Henkel, Lisa M , Krauß, Jürgen , Ebinger, Martin , Schuhmann, Martin , Thomale, Ulrich Wilhelm , Pietsch, Torsten , Klinker, Erdwine , Schlegel, Paul G , Oyen, Florian , Reisner, Yair , Rammensee, Hans-Georg and Eyrich, Matthias
Publisher
England: BMJ Publishing Group Ltd
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Language
English
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Publisher
England: BMJ Publishing Group Ltd
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Contents
BackgroundAtypical teratoid/rhabdoid tumors (AT/RT) are highly aggressive CNS tumors of infancy and early childhood. Hallmark is the surprisingly simple genome with inactivating mutations or deletions in the SMARCB1 gene as the oncogenic driver. Nevertheless, AT/RTs are infiltrated by immune cells and even clonally expanded T cells. However, it is...
Alternative Titles
Full title
Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors
Authors, Artists and Contributors
Author / Creator
Schlosser, Andreas
Keupp, Anne
Trautwein, Nico
Johann, Pascal
Wölfl, Matthias
Lager, Johanna
Monoranu, Camelia Maria
Walz, Juliane S
Henkel, Lisa M
Krauß, Jürgen
Ebinger, Martin
Schuhmann, Martin
Thomale, Ulrich Wilhelm
Pietsch, Torsten
Klinker, Erdwine
Schlegel, Paul G
Oyen, Florian
Reisner, Yair
Rammensee, Hans-Georg
Eyrich, Matthias
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d14d72c4908244119a50f49fe17e6beb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d14d72c4908244119a50f49fe17e6beb
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2021-003404
