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Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in ce...

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1922c4d232445f49f2061be196cfa8a

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

About this item

Full title

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2019-05, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Cancer evolves through a multistep process that occurs by the temporal accumulation of genetic mutations. Tumor-derived exosomes are emerging contributors to tumorigenesis. To understand how exosomes might contribute to cell transformation, we utilized the classic two-step NIH/3T3 cell transformation assay and observed that exosomes isolated from p...

Alternative Titles

Full title

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d1922c4d232445f49f2061be196cfa8a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1922c4d232445f49f2061be196cfa8a

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.40226

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