The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin
The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin
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Author / Creator
Pucci, S , Bonanno, E , Pichiorri, F , Mazzarelli, P and Spagnoli, L G
Publisher
Italy: PAGEPress Publications
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Language
English
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Publisher
Italy: PAGEPress Publications
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Contents
Somatostatin is a peptide hormone that exerts antisecretory and antiproliferative activities on some human tumors. The Ku70/86 heterodimer acts as regulatory subunit of the DNA dependent protein kinase and its DNA binding activity mediates DNA double strands breaks repair that is crucial to maintain the genetic integrity of the genome. The activati...
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Full title
The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin
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TN_cdi_doaj_primary_oai_doaj_org_article_d192f504be974ecdb4531b9f040eba69
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d192f504be974ecdb4531b9f040eba69
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ISSN
1121-760X
E-ISSN
2038-8306
DOI
10.4081/873