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The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin

The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d192f504be974ecdb4531b9f040eba69

The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin

About this item

Full title

The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin

Publisher

Italy: PAGEPress Publications

Journal title

European journal of histochemistry, 2004-04, Vol.48 (2), p.103-110

Language

English

Formats

Publication information

Publisher

Italy: PAGEPress Publications

More information

Scope and Contents

Contents

Somatostatin is a peptide hormone that exerts antisecretory and antiproliferative activities on some human tumors. The Ku70/86 heterodimer acts as regulatory subunit of the DNA dependent protein kinase and its DNA binding activity mediates DNA double strands breaks repair that is crucial to maintain the genetic integrity of the genome. The activati...

Alternative Titles

Full title

The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d192f504be974ecdb4531b9f040eba69

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d192f504be974ecdb4531b9f040eba69

Other Identifiers

ISSN

1121-760X

E-ISSN

2038-8306

DOI

10.4081/873

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