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Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d198e1ab2b18460f8fd9661445a6e392

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Conditional overexpression of histone reader
Tri
partite
m
otif containing protein 24 (TRIM24) in mouse mammary epithelia (
Trim24
COE
) drives spontaneous development of mammary carcinosarcoma tumors, lacking ER, PR and HER2. Human carcinosarcomas or metaplastic breast cancers (MpBC) are a rare, chemorefractory subclass of tri...

Alternative Titles

Full title

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d198e1ab2b18460f8fd9661445a6e392

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d198e1ab2b18460f8fd9661445a6e392

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-25650-z

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