Exploring structural and biological insights of TEAD through rational design and synthesis of niflum...
Exploring structural and biological insights of TEAD through rational design and synthesis of niflumic acid derivatives
About this item
Full title
Author / Creator
Publisher
England: Taylor & Francis Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Taylor & Francis Ltd
Subjects
More information
Scope and Contents
Contents
Transcriptional enhanced associate domain (TEAD) transcription factors undergo auto-palmitoylation, which is critical to mediate their function and maintain stability. Targeting the palmitate binding pocket of TEAD holds considerable promise for drug discovery, and it can be characterised into three components: a conserved cysteine, a hydrophobic m...
Alternative Titles
Full title
Exploring structural and biological insights of TEAD through rational design and synthesis of niflumic acid derivatives
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d1b6d6a6c1ae4cfc87ac106339eee178
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1b6d6a6c1ae4cfc87ac106339eee178
Other Identifiers
ISSN
1475-6366,1475-6374
E-ISSN
1475-6374
DOI
10.1080/14756366.2024.2419925
