RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovar...
RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer
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Author / Creator
Deng, Peng , Wang, Zining , Chen, Jinghong , Liu, Shini , Yao, Xiaosai , Liu, Shaoyan , Liu, Lizhen , Yu, Zhaoliang , Huang, Yulin , Xiong, Zhongtang , Xiao, Rong , Gao, Jiuping , Liang, Weiting , Chen, Jieping , Liu, Hui , Hong, Jing Han , Chan, Jason Yongsheng , Guan, Peiyong , Chen, Jianfeng , Wang, Yali , Yin, Jiaxin , Li, Jundong , Zheng, Min , Zhang, Chao , Zhou, Penghui , Kang, Tiebang , Teh, Bin Tean , Yu, Qiang , Zuo, Zhixiang , Jiang, Qingping , Liu, Jihong , Xiong, Ying , Xia, Xiaojun and Tan, Jing
Publisher
Ann Arbor: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
Ann Arbor: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Prevalent copy number alteration is the most prominent genetic characteristic associated with ovarian cancer (OV) development, but its role in immune evasion has not been fully elucidated. In this study, we identified RAD21, a key component of the cohesin complex, as a frequently amplified oncogene that could modulate immune response in OV. Through...
Alternative Titles
Full title
RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer
Authors, Artists and Contributors
Author / Creator
Wang, Zining
Chen, Jinghong
Liu, Shini
Yao, Xiaosai
Liu, Shaoyan
Liu, Lizhen
Yu, Zhaoliang
Huang, Yulin
Xiong, Zhongtang
Xiao, Rong
Gao, Jiuping
Liang, Weiting
Chen, Jieping
Liu, Hui
Hong, Jing Han
Chan, Jason Yongsheng
Guan, Peiyong
Chen, Jianfeng
Wang, Yali
Yin, Jiaxin
Li, Jundong
Zheng, Min
Zhang, Chao
Zhou, Penghui
Kang, Tiebang
Teh, Bin Tean
Yu, Qiang
Zuo, Zhixiang
Jiang, Qingping
Liu, Jihong
Xiong, Ying
Xia, Xiaojun
Tan, Jing
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d1d685a0f6e94ed4ad24a9147d62ada6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1d685a0f6e94ed4ad24a9147d62ada6
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI159628
