Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and s...
Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and skeletal muscle contractility
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Publisher
Germany: John Wiley & Sons, Inc
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Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Background
About half of heart failure (HF) patients, while having preserved left ventricular function, suffer from diastolic dysfunction (so‐called HFpEF). No specific therapeutics are available for HFpEF in contrast to HF where reduced ejection fractions (HFrEF) can be treated pharmacologically. Myocardial titin filament stiffening, endothelia...
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Full title
Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and skeletal muscle contractility
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TN_cdi_doaj_primary_oai_doaj_org_article_d21b4d9a924d46088cf6607875f92213
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d21b4d9a924d46088cf6607875f92213
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ISSN
2190-5991
E-ISSN
2190-6009
DOI
10.1002/jcsm.12968
