Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling
Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling
About this item
Full title
Author / Creator
Santos-Zas, Icia , Lemarié, Jeremie , Zlatanova, Ivana , Cachanado, Marine , Seghezzi, Jean-Christophe , Benamer, Hakim , Goube, Pascal , Vandestienne, Marie , Cohen, Raphael , Ezzo, Maya , Duval, Vincent , Zhang, Yujiao , Su, Jin-Bo , Bizé, Alain , Sambin, Lucien , Bonnin, Philippe , Branchereau, Maxime , Heymes, Christophe , Tanchot, Corinne , Vilar, José , Delacroix, Clement , Hulot, Jean-Sebastien , Cochain, Clement , Bruneval, Patrick , Danchin, Nicolas , Tedgui, Alain , Mallat, Ziad , Simon, Tabassome , Ghaleh, Bijan , Silvestre, Jean-Sébastien and Ait-Oufella, Hafid
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Acute myocardial infarction is a common condition responsible for heart failure and sudden death. Here, we show that following acute myocardial infarction in mice, CD8
+
T lymphocytes are recruited and activated in the ischemic heart tissue and release Granzyme B, leading to cardiomyocyte apoptosis, adverse ventricular remodeling and deterior...
Alternative Titles
Full title
Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling
Authors, Artists and Contributors
Author / Creator
Lemarié, Jeremie
Zlatanova, Ivana
Cachanado, Marine
Seghezzi, Jean-Christophe
Benamer, Hakim
Goube, Pascal
Vandestienne, Marie
Cohen, Raphael
Ezzo, Maya
Duval, Vincent
Zhang, Yujiao
Su, Jin-Bo
Bizé, Alain
Sambin, Lucien
Bonnin, Philippe
Branchereau, Maxime
Heymes, Christophe
Tanchot, Corinne
Vilar, José
Delacroix, Clement
Hulot, Jean-Sebastien
Cochain, Clement
Bruneval, Patrick
Danchin, Nicolas
Tedgui, Alain
Mallat, Ziad
Simon, Tabassome
Ghaleh, Bijan
Silvestre, Jean-Sébastien
Ait-Oufella, Hafid
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d22cf22ea4844f0bb37075c442f362fe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d22cf22ea4844f0bb37075c442f362fe
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21737-9
