Characterization of cancer-driving nucleotides (CDNs) across genes, cancer types, and patients
Characterization of cancer-driving nucleotides (CDNs) across genes, cancer types, and patients
About this item
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Author / Creator
Zhang, Lingjie , Deng, Tong , Liufu, Zhongqi , Chen, Xiangnyu , Wu, Shijie , Liu, Xueyu , Shi, Changhao , Chen, Bingjie , Hu, Zheng , Cai, Qichun , Liu, Chenli , Li, Mengfeng , Tracy, Miles E , Lu, Xuemei , Wu, Chung-I and Wen, Hai-Jun
Publisher
England: eLife Sciences Publications, Ltd
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Language
English
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Publisher
England: eLife Sciences Publications, Ltd
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Contents
A central goal of cancer genomics is to identify, in each patient, all the cancer-driving mutations. Among them, point mutations are referred to as cancer-driving nucleotides (CDNs), which recur in cancers. The companion study shows that the probability of
i
recurrent hits in
n
patients would decrease exponentially with
i
; hence,...
Alternative Titles
Full title
Characterization of cancer-driving nucleotides (CDNs) across genes, cancer types, and patients
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TN_cdi_doaj_primary_oai_doaj_org_article_d277e2022dba457ba1aa1ec3bbb6ae22
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d277e2022dba457ba1aa1ec3bbb6ae22
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.99341
