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Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metast...

Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metast...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2d11a695913453e8ed1c77cf42a380f

Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metastases

About this item

Full title

Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metastases

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-11, Vol.12 (1), p.20537-20537, Article 20537

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Brain metastases (BMs) in ovarian cancer (OC) are a rare event. BMs occur most frequently in high-grade serous (HGS) OC. The molecular features of BMs in HGSOC are poorly understood. We performed a whole-exome sequencing analysis of ten matched pairs of formalin-fixed paraffin-embedded samples from primary HGSOC and corresponding BMs. Enrichment si...

Alternative Titles

Full title

Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metastases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d2d11a695913453e8ed1c77cf42a380f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2d11a695913453e8ed1c77cf42a380f

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-23788-4

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