miR-29 is an important driver of aging-related phenotypes
miR-29 is an important driver of aging-related phenotypes
About this item
Full title
Author / Creator
Swahari, Vijay , Nakamura, Ayumi , Hollville, Emilie , Hung, Yu-Han , Kanke, Matt , Kurtz, C. Lisa , Caravia, Xurde M. , Roiz-Valle, David , He, Shenghui , Krishnamurthy, Janakiraman , Kapoor, Sahil , Prasad, Varun , Flowers, Cornelius , Beck, Matt , Baran-Gale, Jeanette , Sharpless, Norman , López-Otín, Carlos , Sethupathy, Praveen and Deshmukh, Mohanish
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Aging is a consequence of complex molecular changes, but whether a single microRNA (miRNA) can drive aging remains unclear. A miRNA known to be upregulated during both normal and premature aging is miR-29. We find miR-29 to also be among the top miRNAs predicted to drive aging-related gene expression changes. We show that partial loss of miR-29 ext...
Alternative Titles
Full title
miR-29 is an important driver of aging-related phenotypes
Authors, Artists and Contributors
Author / Creator
Nakamura, Ayumi
Hollville, Emilie
Hung, Yu-Han
Kanke, Matt
Kurtz, C. Lisa
Caravia, Xurde M.
Roiz-Valle, David
He, Shenghui
Krishnamurthy, Janakiraman
Kapoor, Sahil
Prasad, Varun
Flowers, Cornelius
Beck, Matt
Baran-Gale, Jeanette
Sharpless, Norman
López-Otín, Carlos
Sethupathy, Praveen
Deshmukh, Mohanish
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d2e2c9171b5d43a3bb38718b4bf3ccda
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2e2c9171b5d43a3bb38718b4bf3ccda
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-06735-z
