Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations i...
Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop
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Basel: MDPI AG
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English
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Basel: MDPI AG
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The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this work, we have analyzed the effects of selected variants, residing in a structurally unresolved cytoplasmic region (a.a. 354–367) of ABCG2 on the function and...
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Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop
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TN_cdi_doaj_primary_oai_doaj_org_article_d2e751a0cf98473c95d382c7980d6546
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2e751a0cf98473c95d382c7980d6546
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ISSN
2077-0375
E-ISSN
2077-0375
DOI
10.3390/membranes13100822
