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Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type...

Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2f6de543c844e38b53096773b9b25a6

Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

About this item

Full title

Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2024-08, Vol.20 (8), p.e1012426

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Merkel cell polyomavirus (MCPyV) is the causative agent of the majority of Merkel cell carcinomas (MCC). The virus has limited coding capacity, with its early viral proteins, large T (LT) and small T (sT), being multifunctional and contributing to infection and transformation. A fundamental difference in early viral gene expression between infectio...

Alternative Titles

Full title

Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d2f6de543c844e38b53096773b9b25a6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2f6de543c844e38b53096773b9b25a6

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1012426

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