Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular...
Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Background
In this work, the in vitro and in vivo stabilities and the pharmacology of HPMA-made homopolymers were studied by means of radiometal-labeled derivatives. Aiming to identify the fewer amount and the optimal DOTA-linker structure that provides quantitative labeling yields, diverse DOTA-linker systems were conjugated in different amount...
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Full title
Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging
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TN_cdi_doaj_primary_oai_doaj_org_article_d2fa3e625d174a858aa6f3bfbe074e77
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2fa3e625d174a858aa6f3bfbe074e77
Other Identifiers
ISSN
2191-219X
E-ISSN
2191-219X
DOI
10.1186/s13550-018-0372-x
