Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in y...
Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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DNA double-strand breaks (DSBs) activate DNA damage responses (DDRs) in both mitotic and meiotic cells. A single-stranded DNA (ssDNA) binding protein, Replication protein-A (RPA) binds to the ssDNA formed at DSBs to activate ATR/Mec1 kinase for the response. Meiotic DSBs induce homologous recombination monitored by a meiotic DDR called the recombin...
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Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis
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TN_cdi_doaj_primary_oai_doaj_org_article_d310ebb9c6f748008ddb19aab92287db
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d310ebb9c6f748008ddb19aab92287db
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-60082-x