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Optimal futility stopping boundaries for binary endpoints

Optimal futility stopping boundaries for binary endpoints

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d31a9d98394a442a9b42fa55b7e879d5

Optimal futility stopping boundaries for binary endpoints

About this item

Full title

Optimal futility stopping boundaries for binary endpoints

Publisher

England: BioMed Central

Journal title

BMC medical research methodology, 2024-03, Vol.24 (1), p.80-10, Article 80

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Group sequential designs incorporating the option to stop for futility at the time point of an interim analysis can save time and resources. Thereby, the choice of the futility boundary importantly impacts the design's resulting performance characteristics, including the power and probability to correctly or wrongly stop for futility. Several autho...

Alternative Titles

Full title

Optimal futility stopping boundaries for binary endpoints

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d31a9d98394a442a9b42fa55b7e879d5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d31a9d98394a442a9b42fa55b7e879d5

Other Identifiers

ISSN

1471-2288

E-ISSN

1471-2288

DOI

10.1186/s12874-024-02190-w

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