Optimal futility stopping boundaries for binary endpoints
Optimal futility stopping boundaries for binary endpoints
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Publisher
England: BioMed Central
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Language
English
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England: BioMed Central
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Contents
Group sequential designs incorporating the option to stop for futility at the time point of an interim analysis can save time and resources. Thereby, the choice of the futility boundary importantly impacts the design's resulting performance characteristics, including the power and probability to correctly or wrongly stop for futility. Several autho...
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Optimal futility stopping boundaries for binary endpoints
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TN_cdi_doaj_primary_oai_doaj_org_article_d31a9d98394a442a9b42fa55b7e879d5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d31a9d98394a442a9b42fa55b7e879d5
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ISSN
1471-2288
E-ISSN
1471-2288
DOI
10.1186/s12874-024-02190-w