Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated protein...
Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins - towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Mucin type O-glycosylation is one of the most common types of post-translational modifications that impacts stability and biological functions of many mammalian proteins. A large family of UDP-GalNAc polypeptide:N-acetyl-α-galactosaminyltransferases (GalNAc-Ts) catalyzes the first step of mucin type O-glycosylation by transferring GalNAc to serine...
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Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins - towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation
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TN_cdi_doaj_primary_oai_doaj_org_article_d32bc3c9f3ab431993c56d6f91a6a6bc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d32bc3c9f3ab431993c56d6f91a6a6bc
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ISSN
1472-6750
E-ISSN
1472-6750
DOI
10.1186/1472-6750-10-62